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Pharmaceutical chemistry notes

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What makes a good leaving group?

A leaving group is a nucleophile acting in reverse; it accepts a lone pair as the bond between it and its neighbor (usually carbon for our purposes) is broken. So what makes a good leaving group? Good leaving groups are weak bases.

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This page by Professor Hans Reich (UW-Madison) describes some typical nomenclatures commonly encountered in Organic Chemistry. It also provides the names and corresponding structures.

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