Atacama Desert: "In San Pedro de Atacama, an oasis in the heart of the world's driest desert, fine boutique hotels offer excursions to Inca ruins, astronomical observatories, hot springs and much more." Chile Highlights www.bradtguides.com
Santiago, Chile - met a girl from my hometown randomly on the street. Very westernized city. It's like NYC's latin love child. Being on central time made it such an easy adjustment. Practice up on your Spanish though!